Volume 7, Issue 4 (2021)                   Pharm Biomed Res 2021, 7(4): 0-0 | Back to browse issues page

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Alemrajabi M, Dastorani M, Hamidi H, Mohammadian S, Sadrzadeh-Afshar M. Effects of Propolis and Persica Mouthwashes on Three Common Oral Streptococci: A Comparative Study. Pharm Biomed Res. 2021; 7 (4)
URL: http://pbr.mazums.ac.ir/article-1-412-en.html
1- Oral and Maxillofacial medicine department, Faculty of Dentistry, Aja University of medical sciences, Tehran, Iran
2- Endodontics department, Faculty of Dentistry, Aja University of medical sciences, Tehran, Iran
3- Oral and maxillofacial Radiology department, Faculty of Dentistry, Aja University of medical sciences, Tehran, Iran
Abstract:   (191 Views)
Background: Dental caries and periodontal disease are among the most common oral diseases of the present century, and the need for research to achieve an effective strategy to overcome these diseases is clear to everyone. One of these solutions is to use antiseptics and disinfectants, including mouthwashes. Chlorhexidine is the first and most common mouthwash and the gold standard of anti-plaque treatments, but on the other hand it has  many side effects. Herbal mouthwashes can be effective in treating many of these diseases if they have antimicrobial properties and fewer side effects. Objectives:Accordingly, the purpose of this study was to compare the efficiency of these two herbal mouthwashes produced in Iran.
Methods: The present in vitro study was conducted to investigate the antibacterial effects of Persica and Propolis mouthwashes on three standard strains of oral streptococci. The zone of inhibition (ZOI) was measured by disk diffusion method (DDM). The minimum inhibitory concentration (MIC) value of each mouthwash was determined for all microorganisms using macrodilution method.
Results: Statistical analysis of data in DDM showed that the antibacterial effect of Persica was significantly higher than propolis against S. salivarius and S. mutans (P<0.001), and that these two mouthwashes had similar antibacterial effects on S. sanguis. Local propolis exhibited better MIC results than Persica against S. salivarius and S. mutans, and these two mouthwashes showed results similar to each other as for S. sanguis.
Conclusion: According to this study, local propolis has more potential than Persica in preventing the growth of oral streptococci.
Type of Study: Original Research | Subject: Clinical Pharmacy

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