Volume 7, Issue 4 (2021)                   Pharm Biomed Res 2021, 7(4): 0-0 | Back to browse issues page

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Abbaspour Kasgari H, Moradi S, Babamahmoodi F, Shabani A M, Davoodi L, Davoudi Badabi A R. Epidemiologic and Clinical Characteristics of 100 Patients with COVID-19, Admitted to Razi Infectious Disease Referral Centre in Northern Iran in Early 2020. Pharm Biomed Res. 2021; 7 (4)
URL: http://pbr.mazums.ac.ir/article-1-381-en.html
1- Department of Clinical Pharmacy, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
2- Education Development Center, Mazandaran University of Medical Sciences, Sari, Iran
3- Department of Infectious Diseases, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:   (258 Views)
OBJECTIVE
To describe epidemiologic and clinical characteristics of the first cases of the disease referred to a center dedicated to COVID-19 patients in Iran.
DESIGN
 Retrospective cross-sectional study
SETTING
Qaemshahr Razi Hospital in Mazandaran province, northern Iran
PARTICIPANTS
100 confirmed cases with COVID-19, hospitalized from February 25 to March 10, 2020.
MAIN OUTCOME MEASURE
The main demographic data, clinical features including final outcomes, laboratory findings, and data about therapeutic protocols were collected in a structured form and analyzed.
RESULTS
 The mean age of the patients was 56.7±15.6 years. Fifty-nine percent (n=59) of the patients were male. Nineteen percent (n=19) of patients were admitted to the ICU. The median (IQR) of time from disease onset to hospital admission was 5 (3-7) days. The most common symptoms were fever (73%), dyspnea (67%), dry cough (61%) and myalgia (61%). The severity of the disease was moderate in most patients (n=54). The average hospital stay for patients was 7 days. The non-survivor cases in comparison to survived ones were from higher age group (65 y. vs. 52 y., p = 0.001), had a higher frequency of underlying diseases (68.4% vs. 39.5%, p=0.039), had a lower Peripheral capillary o2 saturation at the time of admission (79% vs. 94%, p-value less than 0.001), and were more likely to have Lymphopenia (63.2% vs. 37%, p=0.034).
CONCLUSION
 Lymphopenia, increased Neutrophil to Lymphocyte ratio, and decreased Peripheral capillary o2 saturation are commonly seen in COVID-19 patients, especially among severe cases and can be used in developing clinical prediction rules.
     
Type of Study: Original Research | Subject: Clinical Pharmacy

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