Volume 7, Issue 4 (2021)                   Pharm Biomed Res 2021, 7(4): 0-0 | Back to browse issues page

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Saberi-Hasanabadi P, Ataee R. An overview on adverse effects of the selected drugs currently used in the COVID-19 disease treatment. Pharm Biomed Res. 2021; 7 (4)
URL: http://pbr.mazums.ac.ir/article-1-379-en.html
1- Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari Iran
2- Thalassamia research center, Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari Iran
Abstract:   (143 Views)
Coronavirus disease 2019 (COVID-19), is an ongoing pandemic of coronavirus disease 2019 (COVID‑19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2).  The new coronavirus infection, more commonly referred to as Covid-19, is spreading rapidly around the world with a heavy burden of medical and therapeutic costs on health care facilities. At the time of writing (19 August 2020), no definitive drug treatment for this disease is known. However, the combination of several drugs with other clinical care has had positive results in improving patientschr('39') conditions. The proposed combinations of these medicines could potentially present a safety risk, since most of these drugs have the potential to cause numerous side or toxic effects, even when used as monotherapy.
In this review, we try to mention the latest findings of selected drugs treatments (such as ritonavir, lopinavir, remdesivir, chloroquine, and umifenovir) and their combination used for COVID-19 therapy along with their possible side effects. Clinical observations in terms of possible negative effects on the internal organs of the body in these studies such as hepatotoxicity, retinal damage, and cardiotoxicity in different countries are reviewed in this article.
Type of Study: Review article | Subject: Pharmacology

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