Volume 1, Issue 4 (2015)                   Pharm Biomed Res 2015, 1(4): 59-64 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Asgarirad H, Führer C. Evaluation of the compression process diagram in presence of magnesium stearate . Pharm Biomed Res. 2015; 1 (4) :59-64
URL: http://pbr.mazums.ac.ir/article-1-85-en.html
1- Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
2- Department of Pharmaceutical Technology, TU Braunschweig
Abstract:   (2975 Views)

In the pharmaceutical industry is no longer worked without instrumented tablet presses. The recording of the press information at different parameters of each test series and batches in the development of tablets and an online measurement and control of pressing forces during the production process is becoming increasingly important. Eccentric tablet presses were equipped with sensors for the upper and lower punch force and upper punch way. As sample quantity 100g were selected. All fillers lubricant mixtures were prepared in Turbula lab mixtures with 68 rpm. The bulk and tap density of the excipients were determined according to DIN of 53912 and 53194 on a tap density testers into a 250 ml graduated cylinder. It is to be expected that compression diagrams are changed by lubricant additives. This should give itself to recognize in the different section of the force relationship. This study also showed that the lubricant properties of a lubricant can be greatly influenced by the interaction between the lubricant and ingredient formulation to be exposed.

Full-Text [PDF 319 kb]   (1618 Downloads)    
Type of Study: Original Research | Subject: Pharmaceutics

Add your comments about this article : Your username or Email:

© 2020 All Rights Reserved | Pharmaceutical and Biomedical Research

Designed & Developed by : Yektaweb