Volume 10, Issue 1 (2024)
Pharm Biomed Res 2024, 10(1): 47-56 |
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Ansari A P, Arokiarajan M S, Syed Akbar W A, Ahmed N Z, Anwar N. Investigating the Quality Control, Antimicrobial, and Antioxidant Evaluation of the Ointment “Marham-i-Raal” Used in the Unani System of Medicine. Pharm Biomed Res 2024; 10 (1) :47-56
URL: http://pbr.mazums.ac.ir/article-1-572-en.html
URL: http://pbr.mazums.ac.ir/article-1-572-en.html
Athar Parvez Ansari * 
1, Mary Shamya Arokiarajan1 , Wasim Akram Syed Akbar1 , N Zaheer Ahmed2 , Noman Anwar1
1, Mary Shamya Arokiarajan1 , Wasim Akram Syed Akbar1 , N Zaheer Ahmed2 , Noman Anwar1
1- Regional Research Institute of Unani Medicine, Chennai (NABH Accredited), New Delhi, India.
2- Central Council for Research in Unani Medicine, Ministry of Ayush, Government of India, New Delhi, India.
2- Central Council for Research in Unani Medicine, Ministry of Ayush, Government of India, New Delhi, India.
Abstract: (703 Views)
Background: The global promotion of herbal products is not at par due to a lack of quality control studies. Marham-i-Raal, a pharmacopoeial ointment, treats various types of ulcers and wounds. The present study evaluates the quality control, antimicrobial, and antioxidant properties of Marham-i-Raal.
Methods: The quality control parameters, including loss of weight on drying, pH, total ash value, acid-insoluble ash value, heavy metal analysis, microbial load, and high-performance thin-layer chromatography of Marham-i-Raal, were carried out. Moreover, the antimicrobial and antioxidant activities of Marham-i-Raal were also investigated.
Results: The quality control findings of Marham-i-Raal, including weight loss on drying, pH, total ash value, acid-insoluble ash value, heavy metal analysis, and microbial load, were found within the normal limits. The antimicrobial study of Marham-i-Raal has shown promising effects against gram-positive bacteria and Candida albicans. The antioxidant effects of the test drug were also found to be significant at higher concentrations against 2,2-diphenyl-1-picrylhydrazyl and 2,2’-azino-bis-(3-ethylbenzothiazoline-6-sulfonic) acid methods.
Conclusion: The standards developed for the quality control of Marham-i-Raal may be referred to in the future for further studies. This important Unani ointment may be clinically used to treat non-healing ulcers and wounds.
Methods: The quality control parameters, including loss of weight on drying, pH, total ash value, acid-insoluble ash value, heavy metal analysis, microbial load, and high-performance thin-layer chromatography of Marham-i-Raal, were carried out. Moreover, the antimicrobial and antioxidant activities of Marham-i-Raal were also investigated.
Results: The quality control findings of Marham-i-Raal, including weight loss on drying, pH, total ash value, acid-insoluble ash value, heavy metal analysis, and microbial load, were found within the normal limits. The antimicrobial study of Marham-i-Raal has shown promising effects against gram-positive bacteria and Candida albicans. The antioxidant effects of the test drug were also found to be significant at higher concentrations against 2,2-diphenyl-1-picrylhydrazyl and 2,2’-azino-bis-(3-ethylbenzothiazoline-6-sulfonic) acid methods.
Conclusion: The standards developed for the quality control of Marham-i-Raal may be referred to in the future for further studies. This important Unani ointment may be clinically used to treat non-healing ulcers and wounds.
Type of Study: Original Research |
Subject:
Traditional Medicine
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