Volume 4, Issue 1 ((In Press) 2018)                   mazums-pbr 2018, 4(1): 1-7 | Back to browse issues page

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Mohammadzadeh R, Javadzadeh Y. An overview on oral drug delivery via nano-based formulations. mazums-pbr. 2018; 4 (1) :1-7
URL: http://pbr.mazums.ac.ir/article-1-191-en.html
Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:   (45 Views)
Oral drug administration is used for a large number of medications which are intended to create a systemic effect in the body. Over the recent years, an increasing interest has been offered from pharmacists that led to develop successful formulations for oral drug delivery. But it is still a challenging issue in pharmaceutical technology with many limitations due to the numerous barriers against the absorption and permeability in the gastrointestinal tract. On the other hand, drug carriers play an important role in providing prolonged release and delivery which will then overcome the multiple barriers of maintaining appropriate bioavailability. Alsonanoscaling of the particles, carriers and polymers has provided the capability to characterize and control materials in order to produce unique pharmaceutical components and structures. As well, personalized health care, rational drug design and site-specific targeted drug delivery are some of the profits gained from of a nano-based formulation approach. This review will evaluate a quick overview on some of different types of nanoscaled drug delivery systems which allowed for the delivery of small molecule drugs and in unison of larger particles namely, nucleic acids, peptides and proteins. Delivery of these molecules to exact target areas inside the body can be accomplished, which will decrease systemic adverse effects and allow for more effectual usage of the pharmaceutical preparations.
 
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Type of Study: Review | Subject: Pharmaceutics

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