Volume 3, Issue 3 (September 2017)                   mazums-pbr 2017, 3(3): 12-16 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehrabifard R, Mehdian H, bakhshzadmahmodi M. Effect of non-thermal atmospheric pressure plasma on MDA-MB-231 breast cancer cells . mazums-pbr. 2017; 3 (3) :12-16
URL: http://pbr.mazums.ac.ir/article-1-175-en.html
master of science Department of physics and institute for plasma research, kharazmi University, Mofatteh avenue Tehran, Iran
Abstract:   (551 Views)
Cold atmospheric plasma (CAP) has received great attention due to its noteworthy ability, and has also been widely studied over few decades in physics, biology and medicine. The purpose of this study is to evaluate the cold atmospheric pressure plasma effects on the proliferation of breast cancer cells. MDA-MB-231 was used for this experiment. MDA-MB-231 cells were cultured in 24-well plate and treated with non-thermal plasma. The viability of the cancer cells was determined by MTT assay. Different input power was applied in this experience (20-35W), and treatment time was between 5s and 25s. For reducing thermal damage, gas temperature was less than 37 ˚C. The Viability of breast cancer cells was significantly decreased after plasma treatment. The results showed that viability was decreased with an increment of plasma power and plasma exposure time. These results suggest that non-thermal atmospheric pressure plasma could strongly have cytotoxicity effect on cancerous breast cell.
Full-Text [PDF 1259 kb]   (257 Downloads)    
Type of Study: Research | Subject: Cellular and Molecular Biology

Add your comments about this article : Your username or Email:
Write the security code in the box

Send email to the article author


© 2018 All Rights Reserved | Pharmaceutical and Biomedical Research

Designed & Developed by : Yektaweb