Volume 10, Issue 4 (2024)
Pharm Biomed Res 2024, 10(4): 367-370 |
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Asadi A, Salehi M, Hosseini S H. Investigating Clozapine-induced Sialorrhea Improvement in Highland Climate Area: A Case Study. Pharm Biomed Res 2024; 10 (4) :367-370
URL: http://pbr.mazums.ac.ir/article-1-628-en.html
URL: http://pbr.mazums.ac.ir/article-1-628-en.html
1- 1. Department of Psychiatry, School of Medicine, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
2- Student Research Committee, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
3- Department of Psychiatry, Psychosomatic Research Center, School of Medicine, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
2- Student Research Committee, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
3- Department of Psychiatry, Psychosomatic Research Center, School of Medicine, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Abstract: (212 Views)
Background: This case report describes the elimination of clozapine-induced sialorrhea through a change in residence, highlighting how environmental factors can influence medication side effects.
Case Report: The subject was a 39-year-old woman diagnosed with schizophrenia, who had been experiencing significant sialorrhea as a side effect of clozapine treatment. After relocating to a highland climate, the patient’s excessive salivation was significantly resolved. Importantly, this change occurred without the need for any adjunctive medications, such as atropine, which are commonly prescribed to manage this side effect.
Conclusion: This case underscores the importance of considering environmental factors when evaluating drug effects in patients. It serves as a reminder to healthcare providers to be aware of how changes in a patient’s residence may impact the pharmacodynamics of medications, such as clozapine. Understanding these dynamics can lead to more personalized treatment approaches and improved patient outcomes, emphasizing the need for further investigation into the relationship between climate and medication side effects.
Case Report: The subject was a 39-year-old woman diagnosed with schizophrenia, who had been experiencing significant sialorrhea as a side effect of clozapine treatment. After relocating to a highland climate, the patient’s excessive salivation was significantly resolved. Importantly, this change occurred without the need for any adjunctive medications, such as atropine, which are commonly prescribed to manage this side effect.
Conclusion: This case underscores the importance of considering environmental factors when evaluating drug effects in patients. It serves as a reminder to healthcare providers to be aware of how changes in a patient’s residence may impact the pharmacodynamics of medications, such as clozapine. Understanding these dynamics can lead to more personalized treatment approaches and improved patient outcomes, emphasizing the need for further investigation into the relationship between climate and medication side effects.
Type of Study: case report |
Subject:
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