Volume 9, Issue 2 (2023)
Pharm Biomed Res 2023, 9(2): 163-168 |
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Boskabadi S J, Kargar-Soleimanabad S, Khosravi S, Parsa-kondelaji M, Gholami F. Secondary Hypertension Induced by Vitamin D3: A Case Report and Literature Review. Pharm Biomed Res 2023; 9 (2) :163-168
URL: http://pbr.mazums.ac.ir/article-1-451-en.html
URL: http://pbr.mazums.ac.ir/article-1-451-en.html
Seyyed Javad Boskabadi1 
, Saeed Kargar-Soleimanabad2 , Sahar Khosravi2 , Mohammad Parsa-kondelaji3 , Farhad Gholami * 4
, Saeed Kargar-Soleimanabad2 , Sahar Khosravi2 , Mohammad Parsa-kondelaji3 , Farhad Gholami * 4
1- Department Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
2- Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
3- Department of Hematology and Blood Banking, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
2- Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
3- Department of Hematology and Blood Banking, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Abstract: (1629 Views)
Background: The effects of vitamin D on the skeletal system, biological metabolism, and immune system function are well shown. Cholecalciferol (vitamin D2) and ergocalciferol (vitamin) are 2 major types of vitamin D. Vitamin D3 deficiency is worldwide and the intoxication induced by it is very rare.
Conclusion: Vitamin D3 is involved in calcium hemostasis. The effects of acute hypercalcemia on blood pressure were established. Hypercalcemia can elevate the blood pressure, and renal failure may predispose the individual to a hypertensive response. The clinical symptoms often associated with vitamin D3 intoxication are related to acute renal failure. Hypertension without acute renal failure symptoms can emphasize the relationship between acute hypercalcemia and hypertension.
Conclusion: Vitamin D3 is involved in calcium hemostasis. The effects of acute hypercalcemia on blood pressure were established. Hypercalcemia can elevate the blood pressure, and renal failure may predispose the individual to a hypertensive response. The clinical symptoms often associated with vitamin D3 intoxication are related to acute renal failure. Hypertension without acute renal failure symptoms can emphasize the relationship between acute hypercalcemia and hypertension.
Type of Study: case report |
Subject:
Toxicology
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