Volume 8, Issue 2 (2022)                   Pharm Biomed Res 2022, 8(2): 0-0 | Back to browse issues page

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Kandikattu H K, M.P. V, Narayanappa A, Bilikallahalli Lakshmegowda S, Khanum F. Phytochemical analysis of Cyperus rotundus hexane fraction by GC-MS and total oligomeric flavonoid fraction by 4D GCXGC TOF-MS. Pharm Biomed Res. 2022; 8 (2)
URL: http://pbr.mazums.ac.ir/article-1-385-en.html
1- Tulane Eosinophilic Disorders Center (TEDC), Department of Medicine, Section of Pulmonary Diseases, Tulane University School of Medicine, New Orleans, LA 70112, USA
2- Biochemistry and Nanosciences Discipline, Defence Food Research Laboratory, Mysuru, India
3- Department of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, New Orleans, LA 70112, USA
4- Department of Biotechnology, Sri Jayachamarajendra College of Engineering, Jagadguru Sri Shivarathrishwara Science and Technology University, Mysore, India
Abstract:   (251 Views)
Cyperus rotundus (CR) is a traditional medicinal herb, and recent studies demonstrated its pharmacological effects to cure neurological disorders. In our earlier reports, we also found that CR exerts anxiolytic effects and improves memory impairment in hypoxia-induced rats. In vitro CR also effectively ameliorates oxidative stress-induced SH-SY5Y neuronal cell damage. In the present study, we evaluated the phytochemical composition of hexane fraction, and total oligomeric flavonoid fraction of Cyperus rotundus. The GC-MS analysis showed a variety of chemical constituents in the hexane fraction, and the 4D GCXGC TOF-MS analysis also revealed several phytochemicals present in TOF fraction of C. rotundus. The detected phytochemical constituents of hexane and TOF fraction of C. rotundus may account for the reported pharmacological benefits. The study demonstrates the potential use of CR for the treatment of oxidative stress associated diseases.
     
Type of Study: Original Research | Subject: Natural products

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