en ترکیبات طبیعی Natural products مروری Review article <p><em>Chenopodium botrys</em> L. is native to Europe and Asia and adventive in much of North America. The plant has been used traditionally for medicinal purposes; generally, these therapeutic uses and health benefits of <em>C. botrys</em> are largely based on folklore rather than on scientific substantiation, making it a good candidate to gather documentations, including the phytochemical content, <em>in vitro</em> experiments, animal models and human studies available in the scientific studies. The herb contains flavonoids, alkaloids and several terpenoids. <em>C. botrys</em> of different origins yielded 0.08-2% essential oil. Pharmacological reports support medicinal potential of <em>C. botrys</em> for developing new drugs. Different isomers of ascaridole were identified in <em>C. botrys</em> oil from different origins. In some reports, these compounds were major constituents of the essential oil. Ascaridole has various properties including anthelmintic, antifungal, sedative and pain-relieving. Ascaridole also showed activity against different tumor cell lines <em>in vitro</em>. These data suggest that <em>C. botrys</em> may be an interesting novel candidate plant for cancer treatment, but many studies are needed to confirm this possibility.&shy;</p> Chenopodium botrys L., Traditional uses, Chemical composition, Biological activities 1 9 http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-8&slc_lang=en&sid=1 Katayoun Morteza-Semnani 10031947532846001134 10031947532846001134 Yes Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran