Pregnant women should get the COVID-19 vaccine, said CDC Director Rochelle Walensky, MD, noting that vaccination surveillance systems found “no safety concerns” for more than 35,000 women in their third trimester or for their babies.

She explained that initial vaccine trials did not include pregnant women, so data on possible issues were limited, and the guidance was cautious or even conflicting. “We know that this is a deeply personal decision,” she said. “I encourage people to talk to their doctors and their primary care providers to determine what is best for them and for their baby.”

Peer-reviewed data from national surveillance systems, which were published in a recent issue of the New England Journal of Medicine, back the new recommendation. Between December 14, 2020, and February 28, 2021, data on thousands of pregnant women were collected from CDC's Safe App and the Safe Pregnancy Registry, as well as the vaccine adverse event reporting system. The data show that pregnant women experienced adverse effects similar to those observed in the rest of the population, primarily minor symptoms such as injection site pain, headache, chills, and fever.

Severe reactions were not more common among pregnant women compared with those who were not pregnant, except for nausea and vomiting, which were reported slightly more often among pregnant women following the second dose, according to the research. Early data showed no “obvious safety signals” for pregnancy or neonatal outcomes.
https://www.pharmacytoday.org/article/S1042-0991(21)00373-X/fulltext