Volume 7, Issue 4 (2021)                   Pharm Biomed Res 2021, 7(4): 0-0 | Back to browse issues page

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Kandikattu H K, Narayanappa A, Khanum F, V.V.P.C. N, Doddaga S. A review on Cyperus rotundus: Ancient Weed to Modern Elixer of Life Phytochemistry and therapeutic uses of Cyperus rotundus (Mustaka). Pharm Biomed Res. 2021; 7 (4)
URL: http://pbr.mazums.ac.ir/article-1-384-en.html
1- Tulane Eosinophilic Disorders Center (TEDC), Department of Medicine, Section of Pulmonary Diseases
2- Department of Neuroscience, Tulane University School of Medicine, New Orleans, LA 70112,
3- Biochemistry and Nanosciences discipline, Defence food research laboratory, Mysore-570011, Karnataka, India
4- Department of Chemistry, Sri Venkateswara University, Tirupati-517 502, Andhra Pradesh, India
Abstract:   (170 Views)
Background: Since time immemorial humans identified several herbs for the treatment of various ailments. With the advancement of science and the modern state of the art technologies, various herbal extracts and chemical constituents of herbs were identified as therapeutic targets. Cyperus rotundus also called mustaka is one of the most ancient herbs and is widely distributed in tropical and subtropical regions across the globe. The tuberous and aerial parts of the herb were identified to possess diverse pharmacological activities.
Purpose: The review focuses on the various phytocompounds of musta and how these compounds exert pharmacological effects and their mode of action. The molecular and cellular effects of musta were also discussed based on the pre-clinical and clinical reports available using an array of in vitro, in vivo and ex vivo methodologies.
Conclusion: Based on the literature available on C. rotundus in Google Scholar, Science direct, PUBMED, the pharmacological activities of musta were reviewed with a special focus on its neuropharmacological activity. The mode of action of C. rotundus and its bioactive metabolites on molecular biology level were demonstrated based on data from animal and preclinical experiments to cure various ailments. These diverse effects demonstrate C. rotundus as a valuable traditional medicine for the treatment of various maladies.
 
     
Type of Study: Review article | Subject: Pharmacology

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