http://pbr.mazums.ac.ir en-us Copyright 2005, Academic Web Tools pbr@mazums.ac.ir () pbr@mazums.ac.ir () Sun, 15 Feb 2026 11:13:00 +0330 Sun, 15 Feb 2026 11:13:00 +0330 Yektaweb Collection - https://yektaweb.com http://pbr.mazums.ac.ir/files/site1/site/logo.gif http://pbr.mazums.ac.ir/index.php?sid=1 http://pbr.mazums.ac.ir/content/169/ Bruton tyrosine kinase (BTK) is a protein that plays an important role in the signalling, proliferation, migration and survival of B-cells. For this reason, medicines that target BTK known as BTK inhibitors (BTKis) have been developed as targeted therapies to treat B-cell malignancies​1​. B-cell malignancies are a type of blood cancer that derive from the abnormal development of B-lymphocytes, these encompass a broad range of leukaemias and lymphomas​1​. http://pbr.mazums.ac.ir/find.php?item=1.15.169.en Sun, 15 Feb 2026 11:13:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.169.en Journal News http://pbr.mazums.ac.ir/content/168/ In this episode of Pharmacy Inside Jobs, Sanjay Gudimetla talks about his role as a senior medical affairs manager within the pharmaceutical industry. Careers 29 October 2025 In this episode of Pharmacy Inside Jobs, senior features editor Dawn Connelly talks to Sanjay Gudimetla. http://pbr.mazums.ac.ir/find.php?item=1.15.168.en Sat, 01 Nov 2025 08:43:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.168.en Journal News http://pbr.mazums.ac.ir/content/167/ MEDICINAL cannabis wholesaler Leafio has launched a new program to support pharmacists in learning, upskilling, and confidently dispensing medical cannabis to patients across Australia. The Pharmacy Handbook and Resource Guide provides content to help pharmacists deliver safe, effective and patient-centred care, and features: * information around Australian and global medical cannabis market trends and future outlook * regulatory compliance and secure storage * advice for pharmacists to support patient conversations * step-by-step guides to prepare pharmacies for medical cannabis stocking and dispensing * educational content on terpenes, dosing, and administration methods for edibles, oils, flowers, and vaporisers. http://pbr.mazums.ac.ir/find.php?item=1.15.167.en Mon, 13 Oct 2025 08:47:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.167.en Journal News http://pbr.mazums.ac.ir/content/166/ By Gina Shaw Specialty pharmacists embedded in a pulmonary arterial hypertension (PAH) clinic significantly improved management of side effects and boosted treatment adherence, according to new data presented at the NASP 2025 Annual Meeting & Expo, in Denver. Researchers from the Medical University of South Carolina (MUSC) evaluated interventions for 62 patients treated between January 2024 and April 2025 (poster OPR32-OR). Pharmacists documented 119 interventions addressing electrolyte abnormalities (41), fluid retention (52), medication side effects (25) and hypertension (1). http://pbr.mazums.ac.ir/find.php?item=1.15.166.en Sat, 20 Sep 2025 07:21:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.166.en Journal News http://pbr.mazums.ac.ir/content/165/ Glucagon-like-peptide-1 receptor agonists (GLP-1) are being explored in oncology due to their positive effects on glucose, body fat, insulin resistance, and inflammation, all of which influence cancer progression. While the impact of other glucose-lowering drugs on cancer survival is mixed, newer agents like sodium-glucose cotransporter-2 (SGLT2) inhibitors have been reported to improve survival compared to DPP4 inhibitors. http://pbr.mazums.ac.ir/find.php?item=1.15.165.en Mon, 28 Jul 2025 08:43:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.165.en Journal News http://pbr.mazums.ac.ir/content/164/ Artificial intelligence could alleviate access and resource challenges in small and rural hospitals by streamlining administrative tasks, identifying high-risk patients, improving disease management, facilitating telehealth, and generally allowing these institutions to do more with less, said presenters at the ASHP Midyear 2024 Clinical Meeting and Exhibition, in New Orleans. Gretchen Brummel, PharmD, BCPS, the director of the Professional Experience Program and a clinical associate professor in the Department of Pharmacy Practice and Science at the University of Iowa College of Pharmacy, in Iowa City, described several http://pbr.mazums.ac.ir/find.php?item=1.15.164.en Sat, 17 May 2025 08:07:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.164.en Journal News http://pbr.mazums.ac.ir/content/163/ Home administration of a long-acting injectable antiretroviral therapy (ART) for patients with HIV is as safe and effective as when administered by a health care professional. The investigators of a study by the Medical University of South Carolina also found that patient satisfaction was equally as high compared to the 2 settings.1 http://pbr.mazums.ac.ir/find.php?item=1.15.163.en Mon, 05 May 2025 08:08:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.163.en Journal News http://pbr.mazums.ac.ir/content/162/ The World Health Organization (WHO) classifies the rise in microorganism resistance to existing medications as a matter of global concern that affects the individuals quality of life regardless of economic status or geographical location.1 In 2019 alone, 6.22 million deaths were considered associated with or directly as a result of antimicrobial resistance (AMR). http://pbr.mazums.ac.ir/find.php?item=1.15.162.en Wed, 01 Jan 2025 10:13:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.162.en Journal News http://pbr.mazums.ac.ir/content/161/ Pharmaceutical and Biomedical Research (PBR) is a quarterly international peer-reviewed multi-disciplinary pharmaceutical journal to communicate scientific information in the international pharmaceutical forum. The journal welcomes submitted manuscripts in the broad fields of pharmaceutics, industrial pharmacy, pharmacognosy, toxicology, medicinal chemistry, novel analytical methods for drug characterization, computational and modeling approaches to drug design, bio-medical experience, clinical pharmacy, rational drug prescribing, pharmacoeconomics, biotechnology, nanotechnology, biopharmaceutics, and pharmacology. http://pbr.mazums.ac.ir/find.php?item=1.20.161.en Wed, 13 Nov 2024 11:26:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.20.161.en Call for Papers http://pbr.mazums.ac.ir/content/160/ Findings published in PLoS ONE showcase an in vitro cancer model to investigate why breast cancer spreads to bone. The investigators are optimistic that the method holds promise for advancing the development of preclinical tools to help predict breast cancer bone metastasis. There are about 2.3 million new cases of breast cancer and 700,000 deaths every year, and approximately 80% of patients with primary breast cancer are able to be cured if diagnosed and treated promptly. In many cases, according to the investigators, the cancer has already spread to other parts of the body at the time of diagnosis. http://pbr.mazums.ac.ir/find.php?item=1.15.160.en Wed, 06 Nov 2024 12:01:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.160.en Journal News http://pbr.mazums.ac.ir/content/159/ Routine lung cancer screening with low dose computed tomography (LDCT) could avert morality among high-risk individuals through early detection. Despite lung cancer screening (LCS) recommendations, the disease remains the leading cause of death in the US. To assess the gap of individuals diagnosed compared to individuals that received LCS, researchers conducted a cross-sectional study that evaluated communication for screenings by health care providers among individuals at high risk for lung cancer due to smoking status, demographic, socioeconomic, and clinical characters. http://pbr.mazums.ac.ir/find.php?item=1.15.159.en Wed, 06 Nov 2024 11:58:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.159.en Journal News http://pbr.mazums.ac.ir/content/158/ In an interview, Kristi Veis, PharmD, RPh, vice president of pharmacy at Hi-School Pharmacy, discussed annual influenza vaccinations, the role of the pharmacist in vaccination, and ways pharmacists can increase vaccination rates. Q: For influenza vaccination, who is recommended to get a vaccine, and when is the preferred time frame for getting the vaccination? Kristi Veis: Influenza vaccinations are recommended for all individuals 6 months and older. We allow our pharmacists to decide the youngest patient they feel comfortable vaccinating with the average age of 7 years old. http://pbr.mazums.ac.ir/find.php?item=1.15.158.en Wed, 06 Nov 2024 11:53:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.158.en Journal News http://pbr.mazums.ac.ir/content/157/ The FDA granted an orphan drug designation (ODD) to CAP-002 (Capsida Biotherapeutics) for the treatment of developmental and epileptic encephalopathy (DEE) because of syntaxin-binding protein 1 (STXBP1) mutations. The STXBP1 protein is present in every neuron in the brain and is essential for normal neurotransmission. Mutations in the STXBP1 gene are associated with treatment-resistant seizures, severe developmental delay and intellectual disability, motor abnormalities, and sudden unexpected death in epilepsy. CAP-002 is a novel, first-in-class intravenously (IV) administered gene therapy that uses engineered capsids that are designed to achieve brain-wide neuronal expression of the STXBP1 protein while also significantly detargeting the liver. http://pbr.mazums.ac.ir/find.php?item=1.15.157.en Sat, 02 Nov 2024 14:18:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.157.en Journal News http://pbr.mazums.ac.ir/content/156/ New study findings showed that vitamin D deficiency was common among children undergoing adenotonsillectomy for severe obstructive sleep apnea (OSA), emphasizing the need for further research on vitamin D supplementation to aid pediatric OSA. OSA is a sleep-related disorder breathing disorder that occurs when a blockage in the airway keeps an individual s air from moving through the body while asleep. The blockage causes a lack of airflow that makes blood oxygen levels drop and leads to a survival reflex in the brain that wakes the body slightly to breathe again. http://pbr.mazums.ac.ir/find.php?item=1.15.156.en Sat, 02 Nov 2024 14:08:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.156.en Journal News http://pbr.mazums.ac.ir/content/155/ Martha Rumore, PharmD, Esq, discusses the legal and regulatory complexities surrounding tirzepatide compounding following FDA s removal of the drug from the shortage list, which prompted a lawsuit and led to ongoing uncertainty for 503A and 503B facilities regarding enforcement discretion and future compounding restrictions. This situation creates uncertainty for 503A and 503B compounders. Although the FDA clarified that it intends consistent enforcement discretion for all sterile compounders, 503A compounders remain uncertain about their status. http://pbr.mazums.ac.ir/find.php?item=1.15.155.en Sat, 02 Nov 2024 13:54:00 +0330 http://pbr.mazums.ac.ir/find.php?item=1.15.155.en Journal News