دوره 1، شماره 4 - ( 9-1394 )                   جلد 1 شماره 4 صفحات 1-11 | برگشت به فهرست نسخه ها



DOI: 10.18869/acadpub.pbr.1.4.1

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Soltani M, Ataee R. Proxisome prolifrator-activated receptors alpha and delta in diabetic cardiomyopathy. mazums-pbr. 2015; 1 (4) :1-11
URL: http://pbr.mazums.ac.ir/article-1-73-fa.html
Proxisome prolifrator-activated receptors alpha and delta in diabetic cardiomyopathy. . 1394; 1 (4) :1-11

URL: http://pbr.mazums.ac.ir/article-1-73-fa.html


چکیده:   (988 مشاهده)

Peraxisome prolifrator-activated receptors (PPARs) are a group of nuclear receptors comprising three isoforms termed alpha, beta/delta and gamma. PPARs can modulate metabolic processes especially fatty acid (FA) metabolisms via exerting transcriptional control on activating genes involved in fuel utilization. Thus, they can exert positive role in controlling chronic diseases such as diabetes. As development of diabetes leads to functional and structural alterations at the myocardium termed diabetic cardiomyopathy (DCM), metabolic controller seems to be able to affect on cardiomyocytes. Herein, the role of PPARα, and PPARδ, is emerged and compared. This minireview discusses about these receptors in diabetes.

متن کامل [PDF 447 kb]   (446 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: فارماکولوژی

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Pharmaceutical and Biomedical Research

Designed & Developed by : Yektaweb