Volume 1, Issue 4 (2015)                   Pharm Biomed Res 2015, 1(4): 1-11 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Soltani M, Ataee R. Proxisome prolifrator-activated receptors alpha and delta in diabetic cardiomyopathy. Pharm Biomed Res 2015; 1 (4) :1-11
URL: http://pbr.mazums.ac.ir/article-1-73-en.html
1- Pharmaceutical sciences research center,Hemglobinopathy Institute,Mazandaran Univesrsity of Medical Sciences,Sari Iran
Abstract:   (4083 Views)

Peraxisome prolifrator-activated receptors (PPARs) are a group of nuclear receptors comprising three isoforms termed alpha, beta/delta and gamma. PPARs can modulate metabolic processes especially fatty acid (FA) metabolisms via exerting transcriptional control on activating genes involved in fuel utilization. Thus, they can exert positive role in controlling chronic diseases such as diabetes. As development of diabetes leads to functional and structural alterations at the myocardium termed diabetic cardiomyopathy (DCM), metabolic controller seems to be able to affect on cardiomyocytes. Herein, the role of PPARα, and PPARδ, is emerged and compared. This minireview discusses about these receptors in diabetes.

Full-Text [PDF 447 kb]   (2845 Downloads)    
Type of Study: Review article | Subject: Pharmacology

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Pharmaceutical and Biomedical Research

Designed & Developed by : Yektaweb